A new study suggests that limiting the antioxidant effects of selenium could help prevent the spread of triple negative breast cancer. Selenium, a key antioxidant found in foods such as Brazil nuts, meat, mushrooms, and cereals, was previously thought to be beneficial in fighting against cancer cells. However, the research published in EMBO Molecular Medicine challenges this notion. The study indicates that when triple negative breast cancer cells are not clustered together but instead moving to other parts of the body, they cannot survive without selenium. Dr Saverio Tardito, the lead researcher from the Cancer Research UK Scotland Institute in Glasgow, explains that finding a treatment to interfere with the uptake of selenium by these cancer cells could potentially stop the cancer from spreading.
Selenium is a trace element found in soil and is essential for various bodily functions such as normal thyroid function, immunity, fertility, and protecting the body against cancer and cell damage due to toxins. Due to historically low levels of selenium in UK soils, it is recommended to obtain selenium from sources like animal foods (turkey thigh, beef), fish (tuna), or imported foods like Brazil nuts. A multivitamin and multi-mineral supplement can also be used to complement the diet and ensure adequate selenium intake.
Aside from being a powerful antioxidant, selenium is crucial for maintaining thyroid function and protecting thyroid tissue. Studies also suggest that selenium may help lower cholesterol levels and potentially play a role in cancer prevention and protecting against cognitive decline. However, consuming excessive selenium over a prolonged period can lead to toxicity known as selenosis, resulting in symptoms like hair loss, brittle nails, garlic-like breath, and digestive issues.
The recommended daily intake of selenium is around 60-75μg for adults, with variations depending on life stages such as pregnancy or breastfeeding. While selenium deficiency is rare, an excessive intake of selenium should be avoided, with an upper limit of 400 mcg per day to prevent negative side effects. It is advised to consume three or four Brazil nuts a day or follow dosage instructions when taking dietary supplements to maintain a healthy selenium balance.